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Maili moxibustion can alleviate cancer pain, reduce bone marrow suppression, alleviate gastrointestinal reaction of chemotherapeutic drugs, alleviate cancer-related fatigue, inhibit neurotoxic reaction, improve quality of life and prolong patients' survival. It plays therapeutic effects by regulating immunity, inhibiting tumor cell proliferation and regulating tumor microenvironment. The researches of Maili moxibustion for tumor focus on reducing the toxic or side effects of radiotherapy or chemotherapy. In the future, we should continue to study the combination of Maili moxibustion and other therapies on the treatment of tumor.
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Objective@#To explore the effect of grain-moxibustion combined with routine western medicine therapy on the quality of life of the patients with secondary hyperparathyroidism after hemodialysis.@*Methods@#According to the random number table, 80 hemodialysis patients with secondary hyperparathyroidismin were divided into two groups, 40 in each group. The control group was treated with routine western medicine therapy, while the observation group was treated with grain-moxibustionon the basis of the control group. Both groups were treated for 3 months. Clinical curative effect was evaluated after treatment. The quality of life was assessed by SF-36 Health Survey (SF-36) before and after treatment, serum Ca, P and ALP levels were measured by colorimetry, and intact parathyroid hormone (iPTH) was detected by double antibody sandwich ELISA.@*Results@#Total effective rate was 95.0% (38/40) in the observation group and 80.0% (32/40) in the control group, where there was significantly difference between two groups (χ2=4.114, P=0.043). After treatment, the levels of serum Ca (2.27 ± 0.18 mmol/L vs. 2.07 ± 0.16 mmol/L, t=5.252) in the observation group was significantly higher than that in the control group (P<0.01), the levels of serum P (1.32 ± 0.02 mmol/L vs. 1.60 ± 0.04 mmol/L, t=39.598), iPTH (210.15 ± 16.24 pg/ml vs. 325.41 ± 21.55 pg/ml, t=27.015) and ALP (71.14 ± 10.73 U/L vs. 116.42 ± 12.26 U/L, t=17.577) were significantly lower than those in the control group (P<0.01). After treatment, the scores of physical health, body role function, body pain, overall health score, middle energy, social function, emotional role function and mental health in the observation group were significantly higher than those in the control group (t=2.399, 3.572, 2.684, 3.598, 3.076, 2.811, 4.958, 2.176, P<0.01).@*Conclusions@#Grain-moxibustion combined with routine western medicine therapy in treatment of hemodialysis patients with secondary hyperparathyroidism can adjust the calcium and phosphate metabolic disorders, reduce the parathyroid hormone levels, and they improve the quality of life of patients.
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Objective:To observe the clinical efficacy of moxibustion with seed-sized moxa cone plus opioid drugs for moderate-to-severe cancer pain, and the effect on immune function in patients with cancer pain. Methods: A total of 80 patients with moderate-to-severe cancer pain were randomized into an observation group and a control group by the random number table method, with 40 cases in each group. Both groups were treated with opioid drugs for analgesia according to the standardized management principles for cancer pain. In addition, the observation group was given moxibustion with seed-sized moxa cone. The treatment was performed once a day, continuous 5-day treatment with a 2-day interval constituted a treatment course, and a total of 2 courses were performed. The score of numerical rating scale (NRS) and 24 h equivalent morphine consumption was compared between the two groups before treatment, after 1 treatment course and after 2 courses of treatment. The immune functions were compared between the two groups before and after 2 courses of treatment. Results: During the treatment, there were 3 dropouts in the control group, and 2 dropouts in the observation group. Before the treatment, there were no significant differences in the NRS score and 24 h equivalent morphine consumption between the two groups (both P＞0.05). The NRS scores of both two groups were quite stable during the whole treatment period, and there was no significant difference in the intra-group comparison after treatment (both P＞0.05), and there was no significant difference between the two groups at the same time point (both P＞0.05). In the control group, the 24 h equivalent morphine consumption showed an increasing trend. The dosage after 1 treatment course and 2 courses of treatment was statistically different from that before treatment in the control group (both P＜0.01). There was no significant change in the mean 24 h equivalent morphine consumption in the observation group compared with that before treatment (both P＞0.05). After 2 courses of treatment, the 24 h equivalent morphine consumption in the observation group was significantly lower than that in the control group at the same time point (P＜0.05). Before treatment, there was no significant difference in the levels of T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) between the two groups (all P＞0.05). After treatment, the levels of T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) in the control group were lower than those before treatment (all P＜0.05), while the levels in the observation group were higher than those before treatment, and the levels of CD3+ and CD4+ were significantly different from those before treatment (both P＜0.05). After treatment, the levels of T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) of the observation group were significantly higher than those of the control group at the same time point (all P＜0.05). Conclusion: Moxibustion with seed-sized moxa cone can reduce the dosage of opioid drugs used in patients with moderate-to-severe cancer pain and improve their immune functions.
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Objective To explore the effect of grain-moxibustion combined with routine western medicine therapy on the quality of life of the patients with secondary hyperparathyroidism after hemodialysis. Methods According to the random number table, 80 hemodialysis patients with secondary hyperparathyroidismin were divided into two groups, 40 in each group. The control group was treated with routine western medicine therapy, while the observation group was treated with grain-moxibustionon the basis of the control group. Both groups were treated for 3 months. Clinical curative effect was evaluated after treatment. The quality of life was assessed by SF-36 Health Survey (SF-36) before and after treatment, serum Ca, P and ALP levels were measured by colorimetry, and intact parathyroid hormone (iPTH) was detected by double antibody sandwich ELISA. Results Total effective rate was 95.0% (38/40) in the observation group and 80.0% (32/40) in the control group, where there was significantly difference between two groups (χ2=4.114, P=0.043). After treatment, the levels of serum Ca (2.27 ± 0.18 mmol/L vs. 2.07 ± 0.16 mmol/L, t=5.252) in the observation group was significantly higher than that in the control group (P<0.01), the levels of serum P (1.32 ± 0.02 mmol/L vs. 1.60 ± 0.04 mmol/L, t=39.598), iPTH (210.15 ± 16.24 pg/ml vs. 325.41 ± 21.55 pg/ml, t=27.015) and ALP (71.14 ± 10.73 U/L vs. 116.42 ± 12.26 U/L, t=17.577) were significantly lower than those in the control group (P<0.01). After treatment, the scores of physical health, body role function, body pain, overall health score, middle energy, social function, emotional role function and mental health in the observation group were significantly higher than those in the control group (t=2.399, 3.572, 2.684, 3.598, 3.076, 2.811, 4.958, 2.176, P<0.01). Conclusions Grain-moxibustion combined with routine western medicine therapy in treatment of hemodialysis patients with secondary hyperparathyroidism can adjust the calcium and phosphate metabolic disorders, reduce the parathyroid hormone levels, and they improve the quality of life of patients.
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Objective To observe the clinical efficacy of wheat-sized moxibustion in treating epigastric pain due to deficient cold of spleen and stomach. Method Fifty-six patients were randomized into a treatment group and a control group, 28 cases in each group. The treatment group was intervened by wheat-sized moxibustion; the control group was by orally taking Omeprazole enteric-coated tablets. For both groups, 7 treatment sessions were taken as a course, and the therapeutic efficacies were evaluated after 2 courses. Result There were significant differences in comparing the total effective rate, pain score, and relapse rate between the two groups (P<0.05). Conclusion It can be confirmed that wheat-sized moxibustion is effective in treating epigastric pain due to deficient cold of spleen and stomach, and it can effectively lower the relapse rate and significantly reduce the sufferings brought by the recurred symptoms.
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Objective To observe the clinical efficacy of grain-sized moxibustion in treating cancer-related fatigue and improving the quality of life of patients with malignant tumor. Method Forty-six patients with malignant tumor were randomized into a grain-sized moxibustion group and a control group. The grain-sized moxibustion group received grain-sized moxibustion plus regular treatment, while the control group received the regular treatment only. The cancer-related fatigue intensity [Karnofsky Performance Status (KPS), European Organization for Research on Treatment of Cancer Core Quality-of-life Questionnaire (EORTC QLQ-C30), Piper Fatigue Scale (PFS)], white blood cell count, hemoglobin level, lymphocyte count, and neutrophil count were compared before and after treatment between the two groups. The correlation between cancer-related fatigue and the observed indexes was also analyzed. Result The grain-sized moxibustion group was better than the control group in mitigating the cancer-related fatigue, up-regulating hemoglobin level, and improving the symptoms (P<0.05). Conclusion Grain-sized moxibustion can effectively mitigate cancer-related fatigue via improving anemia condition and the symptoms of malignant tumor patients, and it can also enhance the quality of life of the patients.
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Objective To observe the clinical efficacy of grain-sized moxibustion at Yongquan (KI 1) plus electroacupuncture in treating lumbar intervertebral disc herniation (LIDH).Method Fifty LIDH patients were randomized into a treatment group and a control group, 25 cases in each group. The treatment group was intervened by grain-sized moxibustion plus electroacupuncture, while the control group was by dry electroacupuncture. The Visual Analogue Scale (VAS) and Japanese Orthopaedic Association (JOA) score were observed, and the clinical efficacies were compared.Result After treatment, the VAS and JOA scores were significantly different from that before treatment in both groups (P<0.01). After treatment, the VAS and JOA scores in the treatment group were significantly different from that in the control group (P<0.01,P<0.05). The recovery plus markedly-effective rate and total effective rate were respectively 72.0% and 96.0% in the treatment group, versus 52.0% and 80.0% in the control group, and there was a significant difference in comparing the recovery plus markedly-effective rate (P<0.01).Conclusion Grain-sized moxibustion at Yongquan (KI 1) plus electroacupuncture is an effective approach in treating LIDH.
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ObjectiveBy observing and comparing the effect of wheat-sized moxibustion on the quality of life and interleukin (IL)-10 expression in stageⅢ~Ⅳtumor patients of two different traditional Chinese medicine (TCM) patterns by using QLQ-C30 questionnaire, to see whether wheat-sized moxibustion can improve the quality of life, regulate oncology-related immune system, and enhance the survival rate of the stageⅢ~Ⅳtumor patients.MethodForty-two tumor patients were randomized into a treatment group and a control group and were differentiated into TCM patterns. The treatment group was intervened by conventional Chinese and Western medicine plus 2 weeks of wheat-sized moxibustion. QLQ-C30 questionnaire was adopted for evaluation before and after treatment, and peripheral blood was drawn to detect the expression of IL-10.ResultWheat-sized moxibustion improved the quality of life, especially fatigueand poor appetite; the expression of IL-10 dropped after wheat-sized moxibustion.Conclusion Wheat-sized moxibustion can improve the quality of life of the tumor patients and down-regulate the expression of IL-10.
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Objective To observe the clinical efficacy of grain-sized moxibustion plus acupuncture in treating plantar fasciitis. Method Forty patients with plantar fasciitis were randomized into a treatment group and a control group, 20 in each group. The treatment group was intervened by grain-sized moxibustion plus acupuncture, while the control group was by ordinary acupuncture. Visual Analogue Scale (VAS) was used to observe the morning heel pain degree before and after the treatment, and the clinical efficacies were compared.Result The VAS scores were significantly changed after treatment in the two groups (P<0.05). After treatment, VAS score in the treatment group was significantly different from that in the control group (P<0.05). The recovery rate and total effective rate were respectively 45.0% and 95.0% in the treatment group, versus 10.0% and 90.0% in the control group, and there was a significant difference in comparing the recovery rates (P<0.01).Conclusion Grain-sized moxibustion plus acupuncture is an effective method in treating plantar fasciitis.
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Objective:To observe the clinical effect of acupuncture therapy to support yang and consolidate the constitution for cervical spondylosis of vertebral artery type (CSA). Methods:A total of 72 patients with CSA were randomly divided upon the random digital table into an acupuncture- moxibustion group and an acupuncture group, 36 cases in each group. The acupuncture-moxibustion group was treated by electroacupuncture (EA) at bilateral Fengchi (GB 20) and C4-6 Jiaji (EX-B 2), in combination of moxibustion at Baihui (GV 20), Shenshu (BL 23) and Mingmen (GV 4) to support yang and consolidate constitution. The acupuncture group was given by routine EA at bilateral Fengchi (GB 20), cervical Jiaji (EX-B 2), Tianzhu (BL 10), Jianjing (GB 21), Houxi (SI 3), Hegu (LI 4) and Waiguan (TE 5). The treatment was given once every day and continuous six sessions made one course. After 2-course treatment, the improved situation of clinical symptoms and clinical effect were observed in the two groups. Results:The total effective rate was 91.7% in the acupuncture-moxibustion group and 61.1% in the acupuncture group. The difference of the total effective rate between the two groups was statistically significant (P<0.05). After treatment, the scores of the clinical symptoms in the two groups were obviously decreased than those of the same group before treatment (P<0.01). The differences in the scores between the two groups were statistically significant (P<0.05). Conclusion:Acupuncture-moxibustion treatment to support yang and consolidate constitution is better than the routine acupuncture therapy in the therapeutic effect for CSA.